نویسندگان
Mahdi Heydari, Seyyed Mohsen Seyyedkazemi, Mohammad Taghi Joghataei, Fereshteh Mehraein Ghomi, Hoorieh Mohammadi Kenari, Nader Sadigh, Auob Rustamzadeh, Mehrdad Bakhtiari, Hamidreza Alizadeh-Otaghvar
تاریخ انتشار
2025/1/28
ژورنال
Medical Journal of the Islamic Republic of Iran
جلد
39
صفحات
16
توضیح
Background Inflammation is the first response to tissue damage. A hematoma occurs when blood leaves the damaged vessels, and platelets play an important role in this process. This study aimed to investigate the effect of herbal bioactive compounds on the angiogenic factors and modulation of inflammatory mediators in deep second-degree burn patients. Methods In a randomized clinical trial, 54 patients were divided into two groups :Swalin ointment (n=31) and silver sulfadiazine (SSD) (n=23). Ointments were administered every other day for 28 days. The concentration of compounds in ointment oils was measured using the GC-MS technique. Serum levels of TNF-α and IL-6 were measured on days 3, 7, and 14, and tissue levels of VEGF, FGF, and PDGF variables were measured on day 14 by ELISA method. Student t-test was used to compare the mean in 2 groups, depending on the type of normal/abnormal …