The prevalence of fibrocystic changes of breast tissue of
patients who underwent reduction mammoplasty in
Rasool-Akram, Firuzgar and Sadr Hospitals during
2007-2012

Mostafa Hosseini*
, Adnan Tizmaghz, Hamidreza Alizadeh Otaghvar, Marjan Shams

Abstract: Introduction: Fibrocystic changes are considered as common and benign changes in the breast tissue. This
study aimed to determine the prevalence of pathologic changes Including fibrocystic changes, hyperplasia, and carcinoma
in breast tissue specimens of patients underwent reduction Mammoplasty.Methods: 128 consecutive patients over a period
of 5 years from 2007 to 2012, who were admitted at the Rasool-Akram, Firoozgar, and Sadr Hospitals for reduction
mammoplasty, were investigated in this study. In all patients an average of 500 grams of breast tissue from each side during
mammoplasty was sent for pathologic evaluation. The variables measured in the study included age, fibrocystic changes,
and hyperplastic changes in the pathology specimens of these patients. Data analysis was performed using SPSS 18
software. Results: 71 patients (55.5%) had fibrocystic changes. 6 patients (4.7%) were reported to have hyperplasia.
Carcinoma was not observed in any of the samples. The prevalence of fibrocystic changes increased with age. Hyperplastic
changes were not associated with age and with fibrocystic changes. But it was the most common in the ages between 31
and 40 years. Conclusion: Fibrocystic breast changes are common, and their prevalence increases with age. However, they
are not associated with hyperplasia and cancer risk.