The bioactive compound of traditional herbal ointment accelerates wound closure, epithelialization, and angiogenesis in patients with second-degree burn wound: A randomized …/ژورنال Tissue and Cell جلد 93 صفحات 102787 ناشر Churchill Livingstone

نویسندگان
Mahdi Heydari, Hajir Mehrbani, Seyyed Mohsen Seyyedkazemi, Auob Rustamzadeh, Mohammad Taghi Joghataei, Nader Sadigh, Enam Alhagh Charkhat Gorgich, Hamidreza Alizadeh-Otaghvar
تاریخ انتشار
2025/4/1
ژورنال
Tissue and Cell
جلد
93
صفحات
102787
ناشر
Churchill Livingstone
توضیح
Introduction
This study endeavors to draw a comparative analysis between a traditional herbal ointment, specifically Swalin, and silver sulfadiazine ointment in the context of repairing deep second-degree burns.
Methods
A randomized clinical trial was conducted at the Iran University of Medical Sciences. In this investigation, a cohort comprising eighty-two patients was stratified into two groups, namely Swalin (n = 41) and Silver sulfadiazine (SSD) (n = 41). Over 28 days, ointment applications were administered twice daily. The quantification of ointment compounds was conducted employing Gas Chromatography-Mass Spectrometry (GC-MS). The study encompassed a comprehensive assessment involving clinical examination, quantitative and qualitative histopathological evaluations, pain level determination, and scrutiny of wound closure. Statistical analyses, encompassing chi-square and Mann-Whitney U …

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