Analgesic and Anti-anxiety Effects of the “Direct Lidocaine
Spraying with new Method on Burn Wound due to dressing change

Ali Akbar Jafarian
Mehrdad Shirkavand
Hamidreza Alizadeh Otaghvar
Saeed Amniati
Seyed Hamid Salehi
Fatemeh Jafarian
Homa Faghihi

Abstract
Background and purpose: Burn patients often experience severe pain due to frequent dressing
changes. The purpose of this study is to investigate the effect of 2% lidocaine spray on the level of pain
and anxiety of patients during dressing change.
Materials and methods: A total of 168 patients, including both males and females aged
between 20 and 40 years, were selected from Shahid Motahari Hospital in the year 2017. The participants
in the intervention group were given lidocaine spray, whereas the participants in the control group were
given distilled water spray. Pain scale, Visual Analogue Scale (VAS), anxiety scale, Richmond AgitationSedation Scale (RASS), and heart rate were assessed at 0-3-10 minutes and subsequently every ten minutes.
Results: The average heart rate and diastolic blood pressure in the two groups, up to the tenth
minute after the intervention, were 85.27±3 and 87.29±5, respectively, and in the intervals from zero to
ten minutes, in the control group, it was lower than the control group. The systolic blood pressure, heart
rate and anxiety levels in the 10 to 60 minutes were lower in the intervention group than in the control
group. In 10 and 60 minutes, the average score of pain and anxiety in the intervention group was lower
than the control group. The pain score in the above times was 4.81±1.30, 6.43±0.93, 6.10±1.41, and
8.29±1.68 and the anxiety score was 14.78±1.66, 2.12. It was 17.14±14, 9.92±0.58 and 17.29±2.21.
Conclusion: The findings of the study indicated that Lidocaine spray in the applied
concentration could significantly reduce the pain and the anxiety levels without leading to a significant
change in the systolic blood pressure and the heart rate of the patients.