Effect of Herbal Bioactive Compounds on the Angiogenic Factors and Modulation of Inflammatory Mediators in the Patients with the Deep Second-Degree Burn: A Single-Blinded, Randomized Clinical Trial

Mahdi Heydari , Seyyed Mohsen Seyyedkazemi, Mohammad Taghi Joghataei, Fereshteh Mehraein Ghomi Hoorieh Mohammadi Kenari, Nader Sadigh , Auob Rustamzadeh , Mehrdad Bakhtiari *, Hamidreza Alizadeh-Otaghvar

Abstract
Background
Inflammation is the first response to tissue damage. A hematoma occurs when blood leaves the damaged vessels, and platelets play an important role in this process. This study aimed to investigate the effect of herbal bioactive compounds on the angiogenic factors and modulation of inflammatory mediators in deep second-degree burn patients.